paper of the day:

"A Systems Biology Dynamical Model of Mammalian G1 Cell Cycle Progression"
Thomas Haberichter, Britta Mädge, Renee A Christopher, Naohisa Yoshioka, Anjali Dhiman, Robert Miller, Rina Gendelman, Sergej V Aksenov, Iya G Khalil1 & Steven F Dowdy

The paper describes a combined experimental and computational approach used to understand progression of the mammalian G1 cell cycle, one of the phases in mammalian cell reproduction and tumor growth.
The GNS software was used to quantitatively model the cell cycle progression and then experimentally verified using cultured cells. An excellent example to demonstrate the power of the combinatorial approach.